Potential therapeutic genomic alterations in desmoplastic small round blue cell tumor


Joanne Xiu, Ajaz Bulbul, Sadaf Rashad, Andrea Hayes-Jordan


Desmoplastic Small Round Blue Cell Tumor (DSRCT) originates from a cell with multilineage potential. A molecular hallmark of DSCRT is the EWS-WT1 reciprocal translocation. Ewing’s and DSRCT
are treated similarly due to similar oncogene activation pathways and DSRCT has been represented in very limited numbers in sarcoma studies.

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