Research Proposal Inquiry
Advance Precision Oncology Through Investigator-Initiated Research
The Caris Life Sciences Letter of Intent process empowers members of the Caris Precision Oncology Alliance™ (POA®) to advance innovative, investigator-initiated research. The program is open to academic and community-based physicians and researchers worldwide who are interested in pursuing independent scientific studies which impact patient care and/or contribute to filling a gap in the biological knowledge of cancer.
Participation begins with submission of an inquiry describing the proposed research concept. Inquiries are evaluated based on data availability, test-ability of the hypothesis and lack of overlap with other approved projects. Selected investigators may be invited to submit a Letter of Intent (LOI) full research proposal for further review. Submission of an LOI proposal does not guarantee approval, and all proposals are assessed by the Caris Scientific Review Committee.
Caris is committed to supporting high-quality research and expects all approved studies to result in publication. Any support is contingent upon the successful execution of a research agreement between both parties.
As with all research organizations, our resources are finite. Here are some tips to increase the chance of your proposal to be approved.
Research that we prioritize:
- Hypothesis-driven studies
- Strong data or scientific foundations
- Innovative and translational relevance
Common reasons for rejection:
- Limited data availability in the Caris database for your proposed research question.
- Overlap with ongoing or completed Caris projects.
- Broad Exploratory Descriptive studies without testable hypotheses.
Upon submission, the Caris research team will conduct an initial review and contact you within three business days regarding the outcome and any next steps. For approved inquiries, a link to proceed with the full proposal submission will be provided.
Please visit our LOI resources page for more details.