New discoveries are increasing the number of biomarker/drug associations at an unprecedented rate. It is more important than ever for cancer patients to have comprehensive molecular testing on their tumors.
Whole Exome Sequencing
(Mutations, Indels & Copy Number Alterations)
Whole Transcriptome Sequencing
(Fusions & Variant Transcripts)
Sufficient tumor content (>20% tumor nuclei) must be present to complete all analysis. If you have questions, please contact Customer Support at (888) 979-8669.
Tumor content: >20% tumor nuclei
Paraffin Block (Preferred)
Formalin fixed tissue block (including core-needle biopsies, fine-needle aspirates or malignant fluid)
Unstained Slides
25 slides
10% neutral buffered formalin
Four to six (4-6) biopsies with 18 gauge needle preferred
Six to ten (6-10) biopsies with 22 needle accepted
Approach
Multi-Omic Biomarker Analysis
Biological Coverage
DNA RNA Protein
Variant Coverage
Somatic
Technology
NGS (WES & WTS) IHC ISH PyroSeq
Genes | Depth/Read
22,000 | 500-1000x WES/60M WTS
Whole Exome Sequencing (WES) DNA
SNV INDEL CNA
Whole Transcriptome Sequencing (WTS) RNA
Fusion Variant Transcript
Genomic Signatures
MSI TMB LOH
Other
HLA Genotype*
Enrichment Method
Microdissection
Result Rate
>95%
Turnaround Time
10-14 Days
Specimen Quantity
20% Tumor (NGS) | 1 Slide per IHC/ISH
*Not available in New York state.
The information below details the biomarkers analyzed by technology for the tumor type submitted. Tests may vary if insufficient tumor samples are submitted.
Download Profile Menu for US and Intl PDF >
Use our full gene search to verify that it is included in Caris profiling, or browse the list of genes most commonly associated with cancer.
Search Genes >Whole Exome Sequencing (WES)
Whole Transcriptome Sequencing (WTS)
Select tumor type to see specific tests to be performed.
Immunohistochemistry (IHC) | Other |
---|---|
Additional Information:
Cookie | Duration | Description |
---|---|---|
cookielawinfo-checkbox-analytics | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Analytics". |
cookielawinfo-checkbox-functional | 11 months | The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". |
cookielawinfo-checkbox-necessary | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary". |
cookielawinfo-checkbox-others | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other. |
cookielawinfo-checkbox-performance | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Performance". |
viewed_cookie_policy | 11 months | The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data. |