New discoveries are increasing the number of biomarker/drug associations at an unprecedented rate. It is more important than ever for cancer patients to have comprehensive molecular testing on their tumors.
Caris molecular profiling utilizes a comprehensive approach to assess DNA, RNA and proteins to reveal a molecular blueprint to guide more precise and individualized treatment decisions from among 75+ FDA-approved therapies.
Sufficient tumor content (>20% tumor nuclei) must be present to complete all analysis. If you have questions, please contact Customer Support at (888) 979-8669.
Tumor content: >20% tumor nuclei
Paraffin Block (Preferred)
Formalin fixed tissue block (including core-needle biopsies, fine-needle aspirates or malignant fluid)
Unstained Slides
25 slides
10% neutral buffered formalin
Four to six (4-6) biopsies with 18 gauge needle preferred
Six to ten (6-10) biopsies with 22 needle accepted
Approach
Multi-Omic Biomarker Analysis
Biological Coverage
DNA RNA Protein
Variant Coverage
Somatic
Technology
NGS (WES & WTS) IHC ISH PyroSeq
Genes | Depth/Read
22,000 | 800x WES/23M WTS
Whole Exome Sequencing (WES) DNA
SNV INDEL CNA Karyotyping
Whole Transcriptome Sequencing (WTS) RNA
Fusion Variant Transcript Gene Expression
Genomic Signatures
HRD* gLOH MSI TMB
Other
HLA Genotype*
Enrichment Method
Microdissection
Result Rate
>95%
Turnaround Time
10-14 Days
Specimen Quantity
20% Tumor (NGS) | 1 Slide per IHC/ISH
*Not available in all locations.
Review and download the Caris molecular profiling testing menu for US and International cases.
DownloadReview and download the Caris molecular profiling testing menu for New York state cases.
DownloadReview and download the Caris molecular profiling testing menu for European cases.
Download
"*" indicates required fields
The information below details the biomarkers analyzed by technology for the tumor type submitted. Tests may vary if insufficient tumor samples are submitted.
Whole Exome Sequencing (WES)
Whole Transcriptome Sequencing (WTS)
Select tumor type to see specific tests to be performed.
Immunohistochemistry (IHC) | Other |
---|---|
Additional Information:
Place an order today for a comprehensive, personalized Caris profiling report.
Cookie | Duration | Description |
---|---|---|
cookielawinfo-checkbox-analytics | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Analytics". |
cookielawinfo-checkbox-functional | 11 months | The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". |
cookielawinfo-checkbox-necessary | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary". |
cookielawinfo-checkbox-others | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other. |
cookielawinfo-checkbox-performance | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Performance". |
viewed_cookie_policy | 11 months | The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data. |