Pan-cancer association between increased iron utilization and poor prognosis highlights potential of transferrin receptor-targeting therapies in multiple tumor types

Authors:

Asaad Trabolsi, Artavazd Arumov, Jun Yin, Balazs Halmos, Pavel Brodskiy, Matthew James Oberley, Dave S. B. Hoon, Stephen V. Liu, Shuanzeng Wei, Irene Kang, Jonathan Harry Schatz

Key Finding:

Except for vulvar squamous cell carcinoma, TFRC over-expression is associated with worse overall survival in 23 tumor types. 

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