Pan-cancer association between increased iron utilization and poor prognosis highlights potential of transferrin receptor-targeting therapies in multiple tumor types


Asaad Trabolsi, Artavazd Arumov, Jun Yin, Balazs Halmos, Pavel Brodskiy, Matthew James Oberley, Dave S. B. Hoon, Stephen V. Liu, Shuanzeng Wei, Irene Kang, Jonathan Harry Schatz

Key Finding:

Except for vulvar squamous cell carcinoma, TFRC over-expression is associated with worse overall survival in 23 tumor types. 

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