Molecular profiling identifies genetic heterogeneity in synchronous and asynchronous breast cancers


Windy M. Dean-Colomb, Clayton Yates, PhD, Zoran Gatalica, MD, DSc, Sandeep Reddy, MD, Joyce O’Shaughnessy, MD, Sherri Z. Millis, PhD

Background: Histologic heterogeneity of tumors is well documented; however, the molecular heterogeneity is not well understood, especially relative to driver mutations within clonal populations and their prognostic and predictive value.

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