Does Molecular Landscape differ based on the site of metastasis in Pancreatic ductal adenocarcinoma PDAC

Authors:

Shafia Rahman1, Yasmine Baca2, Harshabad Singh3, Joanne Xiu2, Atrayee B Mallick4, Aaron Ciner6, Mark Rubinstein3, Andrew Aguirre3, George W. Sledge Jr.2, Michael J. Pishvaian5

Background:

  • Liver is the most common site of metastatic spread in PDAC.
  • Liver metastasis (LM) is associated with poor prognosis.
  • Here, we examine the difference in the molecular landscape of PDACs with LM versus other metastatic sites (OM).
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