Differences in Biomarker Expression in HNSCC According to p53 Status

Authors:

Rebecca Feldman, Ph.D., Ariane Kemkes, Ph.D., Joanne Xiu, Ph.D., Richard Blevins, Ph.D., Paula Esmay, M.S., Leslie Battaglia, C.G.(ASCP), C.M., Katrina Radebach, C.G.(ASCP), C.M., Inga Rose, B.S., Curtis Johnston, M.D., Zoran Gatalica, M.D., DSc.

Background

: Patients with p53 wildtype head and neck squamous cell carcinoma (HNSCC) tend to be HPV-positive, which associates with better prognosis. The purpose of this study was to explore biomarker expression profiles for insight into molecular differences in HNSCC patients based on p53 status.

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