Introduction

Epithelial ovarian carcinoma (EOC) is a relatively common malignancy which, by the time it becomes platinum-resistant, contains few good treatment options. Next-generation sequencing (NGS) is a promising technology with the potential to alter how this disease is managed. However, much remains unknown regarding its applicability in ovarian carcinomas. The purpose of this study is to compare metachronous epithelial ovarian carcinoma specimens arising from different sites in an attempt to better understand how to apply NGS in the management of this disease.