Comparative molecular analyses of BRAF-V600E mutant tumors: Colorectal cancers (CRC) vs. melanomas

Authors:

Shelly Ann Christiansen, Rebecca Feldman, Michael B. Atkins, Wafik S. El-Deiry, Ari M. Vanderwalde, Michael J. Pishvaian, Jimmy J. Hwang, Lawrence E. Flaherty, Crystal Shereen Denlinger, Sandeep K. Reddy, John Marshall, Mohamed E. Salem

Background

Little is known about the molecular characteristics of BRAF mutant (mt) CRC. It is unknown whether BRAF mt CRC have molecular and biological profile similar to BRAF mutant melanomas (Mel).

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