Biomarker Analysis of Glioblastoma and Potential Implications for Therapy

Authors:

Joanne Xiu, PhD, Rebecca Feldman-Moreno, PhD, David Arguello, MD, Zoran Gatalica, MD, Anatole Ghazalpour PhD, Ryan P. Bender, PhD, Michael Castro, MD, Sandeep K. Reddy, MD, Gargi D. Basu, PhD, and Les Paul, MD, MS

Background

Glioblastoma multiforme (GBM), the most aggressive CNS cancer, has limited effective therapeutic options, with underlying molecular heterogeneity contributing to the differences in treatment response. Our study was designed to interrogate biomarkers from a large cohort of GBM patients to seek therapeutic implications.

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