Comprehensive Genomic and Transcriptomic Profiling of Acral Lentiginous Melanoma


Gino K. In1, Jun Yin2, Phillip Walker2, Justin Moser3, Joanne Xiu2, Kelsey Poorman2, Geoffrey Thomas Gibney4, Matthew Oberley2, Thuy Phung5, Leonel Hernandez-Aya6, Jose Lustzky6, Wolfgang Michael Korn2, Michael Atkins4


Acral lentiginous melanoma (ALM) is a rare melanoma subtype found on the palms, soles and nailbeds. ALM is poorly responsive to immune checkpoint blockade and outcomes are poor for patients with advanced or metastatic disease. As such, novel treatment approaches are needed.


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