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The Genomic, Transcriptomic, and Immunological Landscape of Sodium-glucose cotrasporter 2 in Lung Cancer and Association with Clinical Outcomes

– Caris Life Sciences

Poster

Conclusions

  • SLC5A2 expression was associated with a highly altered genomic landscape in AC
  • In specific subgroups, high expression of SLC5A2 was associated with OS and TOT with immunotherapy
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  • CRTC1 TRIM11 fusion (CMTCT) tumor with novel presentation in the nasal cavity of three patients

    – Caris Life Sciences

    Manuscript

    Abstract Purpose CRTC1::TRIM11 cutaneous melanocytic tumors are a recently described uncommon entity almost exclusively reported as arising in the skin with fewer than 70 described… […]

  • Differential Impact of Tumor-Derived ESR1 Mutations on Elacestrant Benefit in Metastatic Breast Cancer

    – Caris Life Sciences

    Manuscript

    Abstract Purpose: ESR1 mutations are a well-established mechanism of endocrine therapy resistance in estrogen receptor (ER)–positive metastatic breast cancer and are a biomarker for treatment… […]
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