Inside the Caris Blood Lab
Enabling Precision Oncology Through Scalable Liquid Biopsy
“By integrating high-depth sequencing,
comprehensive nucleic acid analysis, and AI-driven interpretation, the Caris Blood Lab delivers a refined molecular profile to inform precision oncology at scale.”
David Spetzler, MS, PhD, MBA
President
Blood-Based Data
Clinically Actionable Insights from Blood-Based Profiling
The Caris Blood Lab is purpose-built to deliver high-quality, scalable liquid biopsy testing that supports precision oncology across the continuum of care. By leveraging advanced molecular profiling of blood samples, Caris provides comprehensive genomic insights to inform treatment selection and monitor disease in real time.
Using both plasma and buffy coat fractions, Caris differentiates tumor-derived alterations from germline and clonal hematopoiesis signals, providing a more refined and clinically meaningful molecular profile.
Care and Research
Applications Across Clinical Care and Research
Caris Assure® liquid biopsy supports a range of use cases across patient management and scientific advancement:
- Identify actionable somatic alterations to guide targeted therapy selection
- Enable longitudinal testing when tissue biopsy is not feasible
- Support biomarker discovery, patient stratification and translational research efforts
Analysis
End-to-End Analytical Rigor
The Caris Blood Lab integrates stringent operational controls with advanced molecular technologies to ensure accuracy, reproducibility and confidence in every result:
- AI-Driven Interpretation: Artificial intelligence translate complex genomic data into clinically actionable insights
- Chain of Custody Assurance: Continuous high-resolution video monitoring safeguards sample identity and handling integrity
- Comprehensive Genomic Material Extraction: Isolation of diverse genomic materials captures a broad spectrum of molecular alterations
- High-Throughput Sequencing: One of the world’s largest sequencing fleets generates up to 1.6 billion reads per patient
Sequencing
From Sequencing Depth to Clinical Relevance
High-depth sequencing combined with advanced bioinformatics enables detection of low-frequency variants and evolving tumor signals. These capabilities are essential for identifying targets in heterogeneous tumor populations and informing adaptive treatment strategies over time.
Precision
Advancing Precision Oncology
The Caris Blood Lab is a cornerstone of the Caris precision medicine platform, connecting molecular science with clinical decision-making. By integrating liquid biopsy with advanced analytics, Caris helps enable more informed treatment strategies and supports ongoing advancements in cancer research.
Experience the Lab
See how Caris is advancing precision oncology through innovation in liquid biopsy.
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