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Does Molecular Landscape differ based on the site of metastasis in Pancreatic ductal adenocarcinoma PDAC

– Caris Life Sciences

Poster

Background:

  • Liver is the most common site of metastatic spread in PDAC.
  • Liver metastasis (LM) is associated with poor prognosis.
  • Here, we examine the difference in the molecular landscape of PDACs with LM versus other metastatic sites (OM).
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  • Differences in genomic, transcriptomic and immune landscape of prostate cancer (PCa) based on site of metastasis (mets)

    – Caris Life Sciences

    Poster

    Background: In patients with metastatic PCa, specific sites of mets are associated with differential overall survival, with lymph node (LN) only disease having the best… […]

  • Comprehensive molecular profiling of paired patient samples of primary and metastatic (met) pancreatic ductal adenocarcinoma (PDAC)

    – Caris Life Sciences

    Poster

    Introduction: The prevailing thinking about PDAC is that primary and metastatic lesions have similar frequencies of genetic mutations. In addition, metastatic lesions are thought to… […]
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