Key Finding:
Mutations in HRAS are associated with poor outcomes and higher MAPK activation, PD-L1 levels, tumor mutational burden, and IFN scores in head and neck squamous cell carcinomas.
– Caris Life Sciences
Abstract Purpose: 10-15% of prostate cancers (PCa) harbor recurrent FOXA1 aberrations whereby the alteration type and the effect on the forkhead( FKH) domain impacts protein-function. We developed… […]
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