cBioPortal for Cancer Genomics is an open-source platform for interactive, exploratory analysis of large-scale clinicogenomic
data.
The site (https://www.cbioportal.org) hosts data from >390 studies from individual labs and large consortia, including
AACR Project GENIE, which contains >197,000 clinically sequenced samples with clinical annotations like response,
outcome, and treatment history.
A suite of user-friendly visualizations and analyses, including OncoPrints, mutation lollipop plots, variant interpretation,
group comparison, survival analysis, expression correlation analysis, alteration enrichment analysis, and cohort and patientlevel
visualization, enable comprehensive exploration of these data.
cBioPortal is an open source, collaborative effort among groups at Memorial Sloan Kettering Cancer Center, Dana-Farber
Cancer Institute, Childrens Hospital of Philadelphia, Princess Margaret Cancer Centre, Caris Life Sciences, Bilkent University
and The Hyve.
Abstract Conventional and dedifferentiated chondrosarcoma encompass a group of malignant neoplasms that produce cartilaginous matrix and arise within or on the surface of bone. Conventional… […]
Abstract Background: Oncogenic fusions of MAML2 with CRTC1, CRTC3, YAP1, and NR1D1 retain the MAML2 transactivating domain (TAD) and are believed to drive aberrant gene transcription. While the oncogenic roles of these known fusions… […]
