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Adult Granulosa Cell Tumor with Rare Pulmonary Presentation

Abstract

Adult granulosa cell tumor (GCT) is an uncommon sex cord-stromal neoplasm of the ovary. It typically demonstrates locoregional spread, and disease outside of the pelvis as metastasis is uncommon. Only a rare case of primary thoracic adult GCT has been documented, and here we describe another occurrence with unusual pulmonary presentation, thereby expanding the anatomic distribution across which adult GCT could potentially arise.

Highlights

  • Adult granulosa cell tumor (GCT) is an uncommon sex cord-stromal neoplasm that typically arises in the ovary; unusual instances with primary pulmonary presentation and no evidence of pelvic disease have been described.
  • The rare reported cases were notable for locoregional recurrence during their treatment course.
  • While adult GCT has been occasionally known to metastasize to the lungs, the limited number of tumors with a primary thoracic site expand the atomic spectrum over which this cancer is thought to originate
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