
Know early
The blood test designed to detect cancer early, with unmatched accuracy.
Caris Detect™ analyzes every gene in the human body to find evidence of cancer sooner, and with the greatest accuracy available, so patients can act when it matters most.
NOW AVAILABLE (EXCEPT NEW YORK STATE)


WHY EARLY DETECTION MATTERS
Early Cancer Detection can Change Everything.
Caris Detect — the only multi-cancer early detection blood test that analyzes the entire genome — has the ability to detect cancer signals that other tests may miss, even at early stages of disease development.
Powered by advanced Al technology trained on 50 billion molecular markers from more than 1 million real patient cases, Caris Detect is rooted in one of the largest oncological datasets of its kind. Through this depth and breadth of real-world evidence, Caris Detect identifies cancer earlier — and with industry-leading accuracy.
| Stage | Sensitivity |
|---|---|
| Stage I | 56.8% |
| Stage II | 67.7% |
| Stage I-II Combined | 60.3% |
| Stage III | 79.0% |
| Stage IV | 98.6% |
| Specificity | 99.2% in the asymptomatic screening population |
Stop waiting. Start knowing.
The sooner you know, the more power you have to take action. Caris Detect identifies cancer signals before symptoms even appear, when patients still have the greatest number of options — and the most time to act.
Is Caris Detect Right for You?
Caris Detect Eligibility
Intended for:
- Adults 21+
- Individuals concerned about their cancer risk
- Individuals with a family history of cancer
- Individuals who take a proactive approach to understanding their health
Not recommended for:
- Pregnant individuals
- Individuals undergoing active cancer treatment
- Individuals who have received a bone marrow, stem cell, or organ transplant
- Individuals less than three years post-cancer treatment

Your Path to
Answers.
01 Test.
- Convenient patient ordering through our trusted partner, Everlywell, or take a test kit to your provider
- Simple, standard blood draw
- Comprehensive molecular analysis
- Trusted CLIA-certified, CAP-accredited laboratory
02 Know.
- Highly-accurate, actionable results provide confidence in the answer and can help identify the best path forward
- Dedicated Clinical Care support throughout the journey
- Tissue of Origin guidance (when appropriate)
03 Act.
- Accurate path to earlier diagnosis and treatment
- Dedicated patient navigation and support
- Annual screening and prevention planning
Understanding the
Caris Detect Report.
WHAT THIS MEANS
Results will be delivered directly to the patient and ordering healthcare provider. In the results report, Caris Detect recommends that patients review their results with their healthcare provider and develop a personalized cancer prevention and detection plan.
CARIS PROCESSES AND DELIVERS RESULTS
- Caris analyzes the sample using ultra-deep whole genome sequencing and advanced
artificial intelligence.
- Results will be delivered to the ordering provider and patient.
RESULTS REVIEWED WITH PROVIDERS
- The patient brings their results to their provider’s office for clinical interpretation and counsel.
- Provider guides the patient through next steps: specialist referral (if signal detected), monitoring plan (if atypical) or continued routine screening (if not detected).
- Providers can contact Caris Detect Clinical Care for additional support at (855) DETECT-0 (855-338-3280) or CarisDetect@CarisLS.com

No Cancer Signal Detected
WHAT THIS MEANS
No cancer signal was identified at the time of testing.
RECOMMENDED NEXT STEPS
- Continue all routine cancer screening tests recommended for your age, sex, personal medical history and family history, consistent with established guidelines such as those from the U.S. Preventive Services Task Force (USPSTF)1 and the American Cancer Society (ACS).2
- Maintain regular follow-up visits with your healthcare provider and promptly report any new, persistent or
unexplained symptoms or health changes.
- Consider repeating Caris Detect as part of your annual wellness and preventive screening plan in consultation with your healthcare provider.
Atypical Signal Detected
WHAT THIS MEANS
A minor abnormality was found in the blood sample that could be an early cancer signal.
RECOMMENDED NEXT STEPS
- Caris will provide complimentary repeat testing approximately 3 months after your initial Caris Detect result. The Caris Customer Support team will contact you directly to coordinate the blood draw and kit delivery.
- Continue all routine cancer screening tests recommended for your age, sex, personal medical history and family history, consistent with established guidelines such as those from the U.S. Preventive Services Task Force (USPSTF)1 and the American Cancer Society (ACS).2
- Maintain regular follow-up visits with your healthcare provider and promptly report any new, persistent or unexplained symptoms or health changes.
Cancer Signal Detected
WHAT THIS MEANS
Cancer signal was identified at the time of testing.
RECOMMENDED NEXT STEPS
- Review these results with your healthcare provider. Additional testing may be warranted to evaluate for the presence of cancer and could include laboratory studies, imaging and/or referral to a specialist.
- Based on the suspected tissue of origin information included in this report, your healthcare provider may recommend additional targeted screening or diagnostic evaluations.
- Continue all routine cancer screening tests recommended for your age, sex, personal medical history and family history, consistent with established guidelines such as those from the U.S. Preventive Services Task Force (USPSTF)1 and the American Cancer Society (ACS).2
Caris Detect does not detect a signal for all cancers and not all cancers can be detected in the blood. False positive and false negative results may occur. Caris Detect is a companion screening test. It is not a replacement for routine cancer screenings recommended by your healthcare provider. Continue to get regular mammograms, colonoscopies and other routine screenings on your individual risk factors. Talk to your doctor about where Caris Detect fits in your personal health plan.
This test is a laboratory developed test (LDT) that has undergone Clinical Laboratory Improvement Amendments (CLIA) validation. This test is currently available on a cash-pay basis. No insurance coverage is currently available. FSA and HSA accounts may be used. A positive result is not a diagnosis. Results should be interpreted in conjunction with follow-up diagnostic testing and discussion with your healthcare provider.
Email: CarisDetect@CarisLS.com
Phone: 855.338.3280
Address: 4415 Cotton Center Blvd., Suite 100
Phoenix, AZ 85040
*Not available in New York state.
**Imaging reimbursement program: Patients must apply. Eligibility depends on program qualifications and is not guaranteed. The program will not reimburse any covered imaging costs, including copay, coinsurance and/or deductible amounts determined by insurance.
1. U.S. Preventive Services Task Force. USPSTF Recommendation Statements. U.S. Preventive Services Task Force. https://www.uspreventiveservicestaskforce.org. Accessed June 18, 2026.
2. American Cancer Society. Cancer Prevention and Early Detection Guidelines. American Cancer Society. https://
www.cancer.org/health-care-professionals/american-cancer-society-prevention-early-detection-guidelines.html. Accessed June 18, 2026.
3. Caris Life Sciences. Caris Life Sciences Finalizes Achieve 1 Study Results Reinforcing the Superior Sensitivity and Specificity of Caris Detect. News Release. Published March 31, 2026. Data on file.
View full Caris Detect Terms and Conditions.

Stop waiting.
Start knowing.
Caris Detect finds cancer signals in your blood before symptoms ever appear, when survival rates are highest and your options are greatest.
