Key Findings
- In a cohort of cervical cancer patients treated with tisotumab vedotin (TV) who underwent Caris DNA/RNA sequencing, high TF expression was associated with longer overall survival following TV in HPV-negative but not HPV-positive disease.
- This studies highlight how genomic, transcriptomic, immune, and biomarker profiling can refine gynecologic cancer subgroups, inform therapeutic development, and reveal clinically relevant differences in treatment response and outcomes.