Distinct molecular landscape between endometrioid and non-endometrioid uterine carcinoma

Authors:

Nathaniel L. Jones, Joanne Xiu, Sandeep K. Reddy, Ana I. Tergas, William M. Burke, Jason D. Wright, June Y. Hou

Background: Endometrial carcinoma (EC) is typically divided into endometrioid (Type I) and nonendometrioid (Type II) subtypes, despite considerable heterogeneity within each phenotype. We examined molecular alterations between Type I and Type II EC to better understand differences and identify optimal treatment strategies.

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