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Home / Research / Publications / The Genomic, Transcriptomic, and Immunological Landscape of Sodium-glucose cotrasporter 2 in Lung Cancer and Association with Clinical Outcomes

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The Genomic, Transcriptomic, and Immunological Landscape of Sodium-glucose cotrasporter 2 in Lung Cancer and Association with Clinical Outcomes

– Caris Life Sciences

Poster

Conclusions

  • SLC5A2 expression was associated with a highly altered genomic landscape in AC
  • In specific subgroups, high expression of SLC5A2 was associated with OS and TOT with immunotherapy
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  • Clinical and analytical validation of MI Cancer Seek®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay

    – Caris Life Sciences

    Manuscript

    Abstract The precision oncology industry has evolved rapidly within the past two decades, although treatment selection remains a complex undertaking. Access to timely, accurate, and… […]

  • Comparison of trastuzumab deruxtecan and sacituzumab govitecan in HER2-negative metastatic breast cancer: a large real-world data analysis

    – Caris Life Sciences

    Manuscript

    Abstract Background Trastuzumab deruxtecan (T-DXd) and sacituzumab govitecan (SG) are antibody-drug conjugates (ADCs) increasingly used in HER2-negative breast cancer. We hypothesized that treatment benefit would… […]
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