Background
- Claudin 18 (CLDN18) is an emerging biomarker and transmembrane protein that maintains a tight junction between cells in pancreatic cancer (PC).
- Due to the high expression of CLDN18.2, an isoform of CLDN18, genomic profiling has demonstrated CLDN18.2 as a potential target with prognostic impact.
- We aimed to characterize the molecular and immunological features associated with CLDN18.2 expression in PC.