Vulvar and vaginal melanoma – A distinct subclass of melanoma based on a comprehensive molecular analysis of 51 cases


Caitlin Baptiste, William M Burke, Rebecca Feldman, Jason D Wright, Ana I Tergas, June Y Hou

Vulvar melanomas are the second most common vulvar malignancies. These rare cancers are biologically aggressive, and may harbor distinct molecular characteristics from cutaneous and mucosal melanoma of other sites. We analyzed and compared molecular, genomic and protein expression patterns in vulvar/vaginal melanoma (VM) to a large cohort of melanoma of non-gynecological (NGM) origin.

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