Uterine leiomyosarcomas exhibit distinct drug resistance molecular profiles compared to extrauterine leiomyosarcomas – A comprehensive analysis of 1023 leiomyosarcomas

Authors:

Chatterjeea, J. Xiub, S.K. Reddy, N.L. Jones, A. Buckley de Meritens, A.I. Tergas, W.M. Burke, J.D. Wright and J.Y. Hou

Objectives: Controversy exists as to whether uterine leiomyosarcomas (ULMS) and extrauterine leiomyosarcomas (ELMS) represent distinct pathological and molecular entities. We aim to evaluate molecular, genomic, and protein expression patterns in a large cohort of leiomyosarcomas (LMS) in hopes of identifying novel treatment strategies.

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