Tumor profiling of liver metastases (LM) from CRC, NSCLC, pancreatic (PC), breast (BC) and gastroesophageal (GE) tumors to reveal differences versus primary tumors including in cMET, MYC, CDK4, Her2, b-catenin and PD1


Wafik S. El-Deiry, Joanne Xiu, Elias Obeid, Ranee Mehra, Igor A. Astsaturov, Jessica Wagner, Avital Lev, Marie Baumeister, Anthony Frank Shields, Mohamed E. Salem, Jimmy J. Hwang, Namrata Vijayvergia, Crystal Shereen Denlinger, Efrat Dotan, Hossein Borghaei, Michael J. Pishvaian, Philip Agop Philip, John Marshall, Steven J. Cohen, Zoran Gatalica, Sandeep Reddy


Liver is the most common metastatic site for various tumors and associates with poor prognosis. To understand LM as distinct molecularly from other origins such as CRC, NSCLC, BC and GE, we compared a large cohort of LM with local disease (LD) and other metastases (OM).

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