The Heterogeneic Molecular Landscape of Cervical Cancer Metastases (CCM)

Authors:

Matthew J. Hadfield DO1, Sharon Wu, PhD2, Alex Farrell PhD2, Matthew J. Oberley, MD2, Grace Sun MD1, Jody Wellcome MD3, Matthew Anderson MD PhD3, Don Dizon MD1

Background:

  • Cervical Cancer (CC) is a heterogenous disease with multiple histological sub-types.
  • Early screening has led to a significant reduction in disease related mortality, but a significant number of patients present with or progress to advanced disease.
  • Studies between the molecular and immune alterations in CC primaries (CCP) and CC metastases (CCM) are needed to interrogate potential therapeutic strategies.
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