Ovarian carcinosarcoma shares a similar molecular profile as ovarian serous carcinoma but not endometrial carcinosarcoma


Haider Mahdi, Joanne Xiu, Sandeep K. Reddy, Robert Debernardo;


Ovarian carcinosarcomas (OCS) are rare and aggressive malignancies with limited treatment options. It is unclear if this uncommon type of cancer shares similar molecular changes as endometrial carcinosarcoma (ECS) or serous ovarian carcinoma (SOC). We compared the molecular profile of a cohort of OCS to that of SOC and ECS to explore the potential overlap in treatment paradigms.

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