Multiplatform molecular profiling of invasive lobular breast cancer

Authors:

Raquel Nunes, MD; David Arguello, MD; Zoran Gatalica, MD; Sandeep Reddy, MD; Sandra Swain, MD

Background

Invasive lobular breast cancer (ILC) is the second most common subtype of invasive breast cancer accounting for 10% of breast cancer diagnosis. ILC has particular histological and clinical characteristics and a distinct response to therapy. Characterizing the molecular alterations in ILC may lead to an improved understanding of its biology and provide new therapeutic options. The purpose of this study is to describe the molecular profile of ILC and compare it to the one of invasive ductal cancer (IDC).

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