Multi-Omics and Immune Cell Profiling of Metastatic Uveal Melanomas


Justin C. Moser1, Yusra F. Shao2, Joanne Xiu3, Yasmine Baca3, Takami Sato4, Lauren A. Dalvin5, Sourat Darabi6, W. Michael Korn3, Burton Eisenberg6, Geoff Gibney7, Evidio Domingo-Musibay8, Gino In9, Dave Hoon10, Michael Gordon1


Uveal melanoma (UM) is a rare tumor of the eye which is biologically distinct from cutaneous melanoma (CM). Treatment options for patients with metastatic uveal melanoma (mUM) are limited as mUM tends to be resistant to commonly used treatments for cutaneous melanoma. Therefore, a better understanding of the biology of this tumors is needed in order to develop new treatment options. Therefore, we aimed to examine a multi-omics profile of UM as compared to CM.

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