Molecular Profiling of Uveal Melanoma Patients


Zoran Gatalica, Kathleen D Danenberg, Matthew Jerome McGinnis, Anatole Ghazalpour, Ryan P Bender, Raheela Ashfaq, David Arguello, Brian Wright, Nicole Griffin, Gargi D Basu

Background: Although uveal melanoma represents only 5% of all melanomas, it is the most common
primary intraocular malignancy of the adult eye. Approximately 50% of patients will develop metastases
which are resistant to medical interventions. There is a great need for improved therapy as the prognosis
is poor for advanced-stage disease. Our study was undertaken to investigate the presence of novel
therapeutic targets

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