Molecular characterization of colorectal tumors in young patients compared with older patients and impact on outcome


Arielle L. Heeke , Joanne Xiu , Sandeep K. Reddy , Jiji Jiang , Hongkun Wang , John Marshall , Mohamed E. Salem


  • Colorectal cancer (CRC) is increasingly diagnosed in adults <50 years old, often at an advanced stage and with a worse prognosis.
  • Limited data suggests tumors that develop in a younger cohort show distinct genetic changes that are different from classic CRC in older adults. It is unclear how these differences effect clinical outcomes.

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