Molecular and immune landscape of FH-mutated cancers

Authors:

Bayan A Al-Share, Sharon Wu, Abdurahman Alloghbi, Samer Alkassis, Anthony Guastella, Anthony Helmstetter, Chadi Nabhan, Bassel Nazha, Pedro C. Barata, Charles J. Ryan, Rana R. McKay, Elisabeth I. Heath

Key Finding:

FH A41V is the most common variant of unknown significance and is associated with worse survival after chemotherapy compared to other Pathogenic and Likely Pathogenic mutations. 

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