Exploring the nuances between BRCA1 and 2: a multiomic analysis

Authors:

Radhika Gogoi, Sharon Wu, Alex Farrell, Seongho Kim, John Wallbillich, Ira Seth Winer, Robert Morris, David Spetzler, Alberto Puccini, Nathaniel L. Jones, Thomas J. Herzog, Premal H. Thaker, Gil Mor, Ayesha Alvero

Key Finding:

Metabolic and immune response pathways are differentially regulated between BRCA1 mutant, BRCA2 mutant, and homologous recombination wild-type high-grade serous ovarian cancers. 

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