Evaluation of biomarker alterations in small cell cervical cancer identifies therapeutic options


J. K. Burzawa, S. Z. Millis, S. K. Reddy, I. Astsaturov, R. L. Coleman, J. Brown, M. Frumovitz


Small cell cervical cancer (SCCC) is an extremely rare and aggressive form of cervical cancer, accounting for only 1% of all cervical cancer cases, or ~150 cases/yr. 70% of patients will recur, even when diagnosed with early stage disease and there are few therapeutic options in this setting. We evaluated tumor samples obtained from a large repository to determine prevalent targetable molecular aberrations in these rare tumors.

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