Evaluation of biomarker alterations in small cell cervical cancer identifies therapeutic options

Authors:

J. K. Burzawa, S. Z. Millis, S. K. Reddy, I. Astsaturov, R. L. Coleman, J. Brown, M. Frumovitz

Objectives

Small cell cervical cancer (SCCC) is an extremely rare and aggressive form of cervical cancer, accounting for only 1% of all cervical cancer cases, or ~150 cases/yr. 70% of patients will recur, even when diagnosed with early stage disease and there are few therapeutic options in this setting. We evaluated tumor samples obtained from a large repository to determine prevalent targetable molecular aberrations in these rare tumors.

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