Differential expression of biomarkers in gastrointestinal versus pulmonary carcinoid tumors

Authors:

Erika Fong, Gilbert Peterson, Gargi D. Basu, Richard Blevins, Raheela Ashfaq

Background

Carcinoid tumors are endocrine neoplasms that commonly arise in the GI and pulmonary system. About 12,000 cases of carcinoid tumor are diagnosed a year with a 5-year survival rate of 67.2%.The majority of the cases present with advance disease with limited treatment options, therefore evaluation of predictive markers for chemotherapeutic agents is highly desirable. We studied the biomarker expression in carcinoid tumors and evaluated any differences based on site of origin.

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