CXCR4 overexpression: an indicator of poor survival and predictor of response to immunotherapy in patients with metastatic colorectal cancer

Authors:

Sepideh Gholami, Yasmine Baca, Pavel Brodskiy, Joanne Xiu, Gulam Abbas Manji, Andreas Seeber, Anwaar Saeed, Benjamin Adam Weinberg, Moh’d M. Khushman, Rachna T. Shroff, Jim Abraham, Anthony Frank Shields, Heinz-Josef Lenz, John Marshall, Wolfgang Michael Korn, Emil Lou

Key Finding:

Colorectal cancer patients with high tumoral CXCR4 expression had improved survival when treated with pembrolizumab.

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