Comprehensive Characterization of Adrogen Receptor Expression in Breast Cancer

Authors:

Priya Jayachandran, Sachin Deshmukh, Sharon Wu, Kathryn Enriquez, Irene Kang, Joanne Xiu, Alex Farrell, Francesca Battaglin, Pooja Mittal, Janice Lu, Shivani Soni, Wu Zhang, Joshua Millstein, Cynthia Ma, Stephanie Graff, Milan Radovich, Heinz-Josef Lenz, Darcy Spicer, George Sledge, Evanthia Roussos Torres

Background

  • The androgen receptor (AR) is a hormone-regulated transcription factor that plays an important role in breast cancer (BC) pathogenesis.
  • While estrogen receptor inhibitors are well-studied in BC, the role of AR on prognosis and therapy is less well-known.
  • Here we aim to characterize the clinicopathologic and molecular features of AR expression in BC.
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