Comparison of molecular alteration in glioblastoma tumors from old and young patients


Joanne Xiu, Sherise D Ferguson, Sandeep K. Reddy, Santosh Kesari, Stephanie E. Weiss, Raymond J. Hohl, Geoffrey Barger, Amy B. Heimberger


GBM patients (pts.) aged 70 yrs or older have a poorer prognosis than younger pts. IDH1/2 mutations are more prevalent in younger GBM pts. and confer a more favorable prognosis. We compared
molecular alterations between younger pts. (YP; 18 =< age <= 45), and older pts. (OP; age > = 70), with additional stratification for wild type IDH1/2 status.

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