Claudin 18 (CLDN18) gene expression and related molecular profile in gastric cancer (GC)

Authors:

Annika Lenz, Jia Zeng, Joanne Xiu, Sandra Algaze, Priya Jayachandran, Shivani Soni, Jae Ho Lo, Hiroyuki Arai, Wu Zhang, Pavel Brodskiy, Peter Joel Hosein, Benjamin Adam Weinberg, Emil Lou, Anthony Frank Shields, Richard M. Goldberg, John Marshall, Wolfgang Michael Korn, Heinz-Josef Lenz, Francesca Battaglin, Evanthia T. Roussos Torres

Key Finding:

Gastric cancers with high CLDN18 expression display distinct genomic and transcriptomic alterations in immune biomarkers and immune cell infiltration in the tumor microenvironment.

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