Characterization of TP53 Mutations in Actionable Driver-negative Non-Small Cell Lung Cancer NSCLC


Jie Chi, Nishant Gandhi, Balasz Halmos, Stephen Liu, Patrick Ma, Andrew Elliott, Ari Vanderwalde, Hirva Mamdani


  • Despite the increased prevalence in actionable driver-negative (DN) NSCLC, the role ofTP53mutations in this subtype is not fully explored.
  • We characterize the association ofTP53mutations with the molecular and immune landscapes, as well as outcomes, in in the context of histologic subtypes.
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