Age-associated differences in transcriptional expression and tumor immune microenvironment composition among older patients with cancer


Khalil Choucair, Abdul Rafeh Naqash, April K.S. Salama, Chul Kim, Andrew Elliott, Matthew James Oberley, Phillip Walker, Azhar Saeed, Wafik S. El-Deiry, Himisha Beltran, Chadi Nabhan, Stephen V. Liu, Caroline Nebhan, Anwaar Saeed

Key Finding:

Non-small cell lung cancer, melanoma, and renal cell carcinoma samples from patients over 80 years in age are characterized by differential gene expression and changes in tumor microenvironment composition versus tumors from patients less than 80 years in age. 

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