European Urology – Molecular Characterization of Bladder Cancer in Smokers Versus Nonsmokers

Authors:

Monika Joshia, Sherri Z. Millis, David Arguello, Sheldon L. Holder, Donald Lamm, Sandeep Reddy, Chandra Belani, Joseph J. Drabick, Nicholas J. Vogelzang

Abstract

Smoking is considered an important risk factor for bladder cancer (BC), yet molecular characterization of BC in nonsmokers has not been extensively studied. Here, we compare molecular differences between smokers and nonsmokers with BC. BC specimens (676) profiled at a Clinical Laboratory Improvement Amendments-certified laboratory from 2006 to 2014 were retrospectively evaluated for molecular differences between smokers and nonsmokers. protein expression was determined.

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