Comprehensive Genomic Profiling PLUS (CGP+)
With the promise of precision medicine becoming a reality, molecular profiling has become standard of care for many cancer types – and required for certain therapies (companion dx). More than ever, oncologists need a trusted profiling partner to provide reliable, high quality molecular information to guide more precise and individualized treatment decisions.
The Caris Molecular Intelligence® CGP+ approach to assess DNA, RNA and Proteins reveals the highest quality molecular blueprint to guide more precise and individualized treatment decisions that is proven to extend overall survival. As the first and most experienced tumor profiling service, we provide results back in about 8-10 days and to help you find better answers when you need it most.
CGP+ Profiling Technologies
Caris Molecular Intelligence® uses multiple tumor profiling technologies to decode cancer. This technology agnostic, panomic approach allows our medial teams to more fully understand the biology of the tumor – therefore helping oncologists’ better plan their attack.
Immunohistochemistry (IHC): determines level of protein expression
in situ Hybridization: detects gene deletions, amplifications, translocations and fusions
Next-Generation Sequencing (NGS): rapidly examines and more broadly detects DNA mutations, copy number variations and gene fusions across the genome
Sanger Sequencing: examines strands of DNA to identify mutations by analyzing long contiguous sequencing reads
Pyro Sequencing (PyroSeq): detects and quantifies mutations, methylation, etc. through sequencing by synthesis
Fragment Analysis (FA/Frag. Analysis): detects changes in DNA or RNA to indicate the presence or absence of genetic marker